Development of a Decision Support System for Exosome Therapy Dosing
A novel approach based on Agentic AI to support personalized treatment in Premature Ovarian Insufficiency (POI).

Introduction to Exosome Therapy and Its Benefits
Exosome therapy is one of the novel and leading approaches in the field of stem cell-based therapies. In this method, instead of using stem cells directly, exosomes are utilized. Exosomes are extracellular vesicles secreted by these cells, responsible for transmitting biological messages and stimulating tissue repair and regeneration processes.
Due to having many of the benefits of cell therapy while reducing some of its limitations and risks (such as unwanted immune reactions), this method has been proposed as a highly promising option for treating various diseases, including Premature Ovarian Insufficiency (POI).
Challenges and the Necessity of Using AI
Despite the high potential of exosome therapy, this field is still emerging. Existing clinical studies are limited, and comprehensive, standardized knowledge regarding the determination of the optimal therapeutic dose for patients with different physiological conditions is incomplete.
In such circumstances, where physicians face a lack of precise dosing protocols, advanced AI technologies can play a significant role in aggregating and analyzing existing knowledge and supporting sensitive therapeutic decisions.
Agent-Based Decision Support System Approach
The main goal of this research is to develop an advanced decision support system based on Agentic AI for determining the exosome therapy dose in patients with Premature Ovarian Insufficiency.
How the System Works:
Achievements and Future Prospects
This research is expected to pave new paths in medical science by effectively using the analytical power of smart agents:
Reducing Uncertainty
Improving the therapeutic dosing process and reducing errors caused by guesswork in complex medical decision-making.
Personalized Treatment
Developing and promoting exosome-based Personalized Medicine, perfectly tailored to each patient’s needs and conditions.
Accelerating Clinical Application
A major step toward deploying the next generation of agent-based smart systems in medicine, accelerating the development of clinical applications in modern therapies.